Selected lab publications
Ramirez MA, Ninoyu Y, Miller C, Andrade LR, Edassery S, Bomba-Warczak E, Ortega B, Manor U, Rutherford MA, Friedman RA, Savas JN. (2022) Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. iScience Jul 20;25(8):104803. PMID: 35992071
Bomba-Warczak E, Edassery SL, Hark TJ, Savas JN. (2021) Long-lived mitochondrial proteins as pillars of cristae architecture.J Cell Biol. 2021 Sep 6;220(9):e202005193. PMID: 34259807
Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E, Nomura T, O’Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, Steinhauser ML, Stowell MHB, Chapman ER, Contractor A, Savas JN. Pulse-chase Proteomics of App Knock-In Mice Reveals Synaptic Dysfunction Originates in Presynaptic Terminals Cell Systems 2021Feb 17;12(2):141-158. PMID: 33326751
Jongkamonwiwat N*, Ramirez MA*, Edassery S, Wong ACY, Yu J, Abbott T, Pak K, Ryan AF, Savas JN. Noise exposures causing hearing loss generate proteotoxic stress and activate the proteostasis network. Cell Rep. 2020 Nov 24;33(8):108431 PMID:33238128
Hickox AE*, Wong AC*, Pak K, Strojny C, Ramirez M, Yates JR 3rd, Ryan AF, Savas JN. Global Analysis of Protein Expression of Inner Ear Hair Cells. J Neurosci. 2017 1;37(5):1320-1339. PMID: 28039372
Complete list of publications can be found here
Other publications
Savas JN#, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR 3rd#. (2017) Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology. Cell Rep. 21(9):2614-2627. # corresponding authors.
Savas JN, Ribeiro LF, Wierda KD, Wright R, DeNardo-Wilke LA, Rice HC, Chamma I, Wang YZ, Zemla R, Lavallée-Adam M, Vennekens KM, O’Sullivan ML, Antonios JK, Hall EA, Thoumine O, Attie AD, Yates JR 3rd, Ghosh A, de Wit J. (2015) The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors. Neuron. Aug 19;87(4):764-80.
Toyama BH*, Savas JN*, Park SK, Harris MS, Ingolia NT, Yates JR 3rd, Hetzer MW. (2013) Identification of long-lived proteins reveals exceptional stability of essential cellular structures. Cell. 154 (5): 971-82.
Savas JN*, Toyama BH*, Xu T, Yates JR 3rd, Hetzer MW. (2012) Extremely long-lived nuclear pore proteins in the rat brain. Science. 335(6071):942.
*Equal contribution.